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Fig. S4
fih-1regulates hif-1a targets during zebrafish development.
(A) Schematic diagram on negative regulation of Hif-1α by Fih-1. Whole-mount in situ hybridization of heme oygenase1a (hmox1a) (B) and glucose transporter-3 (glut3) (C) in control or fih-1 MO-injected embryos. Lack of Fih-1 strongly induces expression of known Hif-1α targets.
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