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Fig. 8
Activity of rab5ab in endocytosis. Transverse sections of cells of the leading edge of the enveloping layer from a 3 ng control-injected embryo 80% epiboly (A) and (C), a 3 ng rab5ab MO injected embryo (fixed at 40% epiboly but when control embryos were at 80% (B) and (D). White arrows show large secondary lysosomes with membranous contents. (A) and (B) are at 10,000×; and (C) and (D) are at 18,750×.
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Reprinted from Developmental Biology, 397(2), Kenyon, E.J., Campos, I., Bull, J.C., Williams, P.H., Stemple, D.L., Clark, M.D., Zebrafish Rab5 Proteins and a role for Rab5ab in nodal signalling, 212-24, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.