ZFIN Image: Maier et al., 2014, Fig. S2

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Figure Caption

Fig. S2 Patterning of the otic vesicle in the aldh1a2^-/- (neckless/nls) mutant at 26 hpf. (A–E) Expression of non-neural markers tbx1 (n = 14/19 from a heterozygous cross) and otx1 (n = 39/52), the neuronal marker neurod1 (n = 44/57), and the sensory markers sox2 (n = 45/59) and atoh1a (n = 9/13) are normal in the OV of sibling embryos. (F–J) In aldh1a2^-/- (nls) mutants, patterning is relatively normal for all markers tested. Expression of tbx1 (n = 5/19) and otx1 (n = 13/52) is shifted slightly posteriorly, neurod1 (n = 13/57) expression is slightly increased and shifted more posteriorly and expression of sox2 (n = 14/59) and atoh1a (n = 4/13) is normal. All panels are lateral views with anterior to the left. Scale bar: 50 µm.

Acknowledgments

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