ZFIN Image: Maeda et al., 2014, Fig. S10

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Figure Caption

Fig. S10 Decreased mechanosensitive responses of hair cells stably expressing Tmc2a^1–260-GFP-CAAX at 3 dpf. (A–A′′) Example of expression of the 260-aa N-terminal fragment in lateral-line hair cells. The bright oval-shaped puncta of exogenous Tmc2a fragments are enriched in apical hair bundles at the center of the rosette, although more label is present in the soma in comparison with the 117-aa fragment (Fig. S9). (Scale bar: 5 μm.) (B–D) Calcium transients in lateralline hair cells in response to 0.1-, 0.5-, and 1.0-s deflections. (E) Summary of responses normalized to transgenic R-GECO1 control hair cells.

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Acknowledgments

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