Fig. 7
Knockdown of p75, TROY, or Nogo-C2/NgRH1a resulted in disordered morphogenesis of the PLL primordium during caudal migration.
(A) Transgenic CldnB::lynEGFP zebrafish were injected with control MO (panel a), or MOs against zebrafish p75 (panel b), TROY (panel c), or Nogo-C2/NgRH1a (panel d), and time-lapse recording was then performed from 28 hpf. The morphology of PLL primordium in the morphants was unstable during migration, as shown at 30-min intervals (panels b–d). (B) Rosette formation in control (panel a), p75 (panel b), TROY (panel c), and Nogo-C2/NgRH1a (panel d) morphants. Rosettes are indicated by red arrows. Scale bar, 20 μm.