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Fig. S2
Non-overlapping sfrp1a and sfrp5 morpholinos display similar ocular phenotypes. Embryos injected with combinations of morpholino oligonucleotides (MO) (3 ng each) are analyzed for eye size and morphology at 48 hpf (A-D). The MOs were designed as either translation or splice blocking, with sfrp1a MO1 and MO2 splice blocking, and MO3 translation blocking. sfrp5 MO1 is splice blocking while MO2 is translation blocking.
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Reprinted from Developmental Biology, 388(2), Holly, V.L., Widen, S.A., Famulski, J.K., and Waskiewicz, A.J., Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development, 192-204, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.