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Fig. S3 Proliferation and cell death in mmp17b knockdown embryos. A and B are structures of MMP inhibitors Marimastat and ONO-4817 used in this study. C-E are TUNEL assay staining performed on uninjected (UI) (C) and mmp17b MO1 (E) injected 26 hpf embryos. A 26 hpf control MO injected embryo treated with 6 mM H2O2 (D) was included as a positive control. F-H are phosphohistone H3 (pH3) staining performed on control MO (F), mmp17b MO1 G), and mmp17b MO2 (H) injected 26 hpf embryos. No difference was observed in mmp17b KD embryos compared to controls.
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