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Fig. 4 Aβ-deficiency induced by BSI-treatment caused vascular defects that were rescued by Aβ, but not p3.Vascular abnormalities in zAPP-MO could be discerned in embryos at 2 dpf. Fluorescence (top) and confocal (bottom) microscopy of 2 dpf embryos. (A) control uninjected embryo. (B) Embryo injected with scrambled sequence morpholino oligonucleotides (ctrl-MO). (C) Embryo injected with zAPP-targeting morpholino. Note CtA emerging from the lateral PHBC on the left side of A and B, but not C.
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