Image
|
Figure Caption
Fig. S2
Dvr1 LR phenotype is not rescued by p53 morpholino. (A)–(E) At 24, Dvr1 AUG and Sp morphants (B) and (C) show a head necrosis phenotype that can be rescued by coinjection of p53 morpholino suggesting that this phenotype is nonspecific. (F)–(J) At 48 hpf nonspecific morpholino phenotypes in both Dvr1 AUG and Sp morphants (G) and (I) can also be rescued by p53 morpholino co-injection. (K)–(S) The reduced or absent expression of the left-sided LPM marker, spaw, in Dvr1 AUG and Sp morphants is a Dvr1 morpholino specific phenotype and cannot be rescued by co-injection with p53 morpholino co-injection.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 382(1), Peterson, A.G., Wang, X., and Yost, H. J., Dvr1 transfers left-right asymmetric signals from Kupffer's vesicle to lateral plate mesoderm in zebrafish, 198-208, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.