ZFIN Image: Peterson et al., 2013, Fig. 7

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Figure Caption

Fig. 7

Charon inhibits Spaw but not BDvr1. (A) Endogenous gsc expression in control GFP mRNA injected zebrafish embryos. (B) spaw mRNA alone expands the gsc expression domain while co-injection of either (C) charon mRNA or (D) lefty1 mRNA suppresses the gsc expression enhancement caused by spaw alone. (E) Injection of Bdvr1 mRNA expands the expression domain of gsc. (F) Coinjection of charon with Bdvr1 cannot block the ectopic expression of gsc induced by Bdvr1 even when charon mRNA is injected at 10 times the concentration as that able to suppress ectopic gsc expression caused by spaw. (G). Lefty1 coinjection with Bdvr1 is able to suppress the ectopic gsc expression caused by Bdvr1. (H) Quantification of gsc expression patterns in injected embryos.

Acknowledgments

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Reprinted from Developmental Biology, 382(1), Peterson, A.G., Wang, X., and Yost, H. J., Dvr1 transfers left-right asymmetric signals from Kupffer's vesicle to lateral plate mesoderm in zebrafish, 198-208, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.