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Figure Caption
Fig. 1 Localization of activated CaMK-II in 24–72 hpf zebrafish embryonic ears. Embryos were immunostained for P-CaMK-II (A, D, G, J, M, P, S, V) in wild-type or CAAX:GFP embryos and then counterstained for acetylated tubulin (B, Q, T, W), F actin (H), γ tubulin (K) or HCS-1 (N). Arrowheads point to the most intense P-CaMK-II staining. Images were acquired laterally with anterior to the left at 24 hpf (A–L), 36 hpf (M–O), 48hpf (P–R) or 72 hpf (S–X). am=anterior macula, ac=anterior crista. All scale bars=5 μm.
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Reprinted from Developmental Biology, 381(1), Rothschild, S.C., Lahvic, J., Francescatto, L., McLeod, J.J., Burgess, S.M., and Tombes, R.M., CaMK-II activation is essential for zebrafish inner ear development and acts through Delta-Notch signaling, 179-88, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.