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Fig. S8
Increased size of blood vessels in the liver of tsc2 homozygous mutant zebrafish. The tsc2 mutant allele was crossed to transgenic fish expressing EGFP under the Fli1 promoter that directs expression in endothelial cells. Examples shown are liver from 7 day old larvae. Above images are wildtype (wt) control, below are tsc2 homozygous mutant sections. Left images are Fli1:EGFP, and right images hematoxylin and eosin staining. Asterisks (yellow in Fli1:EGFP, black in hematoxylin and eosin stain) denote the blood vessel lumen. Scale bar = 100 μm.
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Full text @ Dis. Model. Mech.