IMAGE

Fig. 3

ID

ZDB-IMAGE-130802-11

Genes

mAGFP
mKOFP2

Antibodies

Ab3-prox1

Source

Figures for Koltowska et al., 2013

Image

Figure Caption

Fig. 3 Ssrp1a promotes cell cycle progression. (A-C) BrdU incorporation is reduced in ssrp1a^s819 mutant livers from 38 hpf onwards (outlined). Error bars represent s.d. (D-G) Transgenic cecyil expression marks G₁ phase cells in red and S/G₂/M phase cells in green. (H) Quantification of hepatoblast proliferation shows a reversed distribution in controls and ssrp1a^s819 mutants at 48 hpf. (I) FACS analysis of 42-44 hpf foregut endoderm shows an increase of cells in S phase and a decrease of those in G₁ phase in ssrp1a^s819 mutants. A-B′,D-G are confocal projections of ventral views; all anterior to the top. ^*P<0.05, ^***P<0.0005, determined by unpaired Student’s t-test.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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