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Fig. S4 Dosedependent reduction of trypsin expression following genetic and morpholino-based loss of isl gene function at 76 hpf. Examples of trypsin mRNA stainings that were summarized in Fig. 5C. Shown are control (A–D) and isl1 mutant embryos (E–H) that were injected with indicated combinations of isl2a and isl2b morpholinos. Images show a dorsal view with anterior to the left. (I) Quantification of the length of trypsin mRNA expression in control and isl1 mutant embryos injected with the indicated morpholinos. Bars show mean+SEM.
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Reprinted from Developmental Biology, 378(1), Wilfinger, A., Arkhipova, V., and Meyer, D., Cell type and tissue specific function of islet genes in zebrafish pancreas development, 25-37, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.