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Fig. S7
Extracellular Domain of EpCAM Is Active to Modulate Wnt Signaling in Lateral Line Primordia. related to Figure 7
Expressions of fgf3 (A and B) and dkk1b (E and F), downstream factors of Wnt signaling in the lateral line primordia, are completely missing in hi2151 mutant embryos, which can be rescued by the injection of epcam (C and G) or epcam ECD mRNA (D and H).
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Reprinted from Developmental Cell, 24(5), Lu, H., Ma, J., Yang, Y., Shi, W., and Luo, L., EpCAM Is an Endoderm-Specific Wnt Derepressor that Licenses Hepatic Development, 543-553, Copyright (2013) with permission from Elsevier. Full text @ Dev. Cell