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Fig. S4 Loss-of-function of plcg1 does not affect the balance between erythropoiesis and myelopoiesis. ((A)–(D)) Expression of gata1 ((A) and (B)) and pu.1 ((C) and (D)) have no difference in plcg1 mutants compared with siblings at 18 hpf. ((E)–(H)) WISH for mpx. Sumo123 MOs cannot rescue mpx expression in plcg1 mutants. Wild-type siblings injected with sumo MO have increased mpx expression compared with control ((E) and (G), black arrows). But in plcg1 mutants, sumo MOs fail to rescue mpx expression ((F) and (H)).
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Reprinted from Developmental Biology, 374(1), Jing, C.B., Chen, Y., Dong, M., Peng, X.L., Jia, X.E., Gao, L., Ma, K., Deng, M., Liu, T.X., Zon, L.I., Zhu, J., Zhou, Y., and Zhou, Y., Phospholipase c gamma-1 is required for granulocyte maturation in zebrafish, 24-31, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.