Fig. 4

Fig. 4 Localization of EphrinB2a suggests gradual loss of segment polarity after loss of both rap1b and itg±5 function. Dorsal views (A–C:) and higher magnification dorsal views (A’–C’’) of EphrinB2a protein localized to the posterior halves of somites in (A–A’’) wild-type and (B–B’’) rap1b MO1 embryos. Localized EphrinB2a is lost in anterior somites of (C–C’’) itg±5^/; rap1b double morphants, but is transiently present in more recently formed posterior somites. Shown are 12–15-somite-stage zebrafish embryos. In A–C, anterior is up, while in A’–C’’ anterior is left.