ZFIN Image: Lalwani et al., 2012, Fig. S1

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Figure Caption

Fig. S1 Microinjection of miR-142a-3p morpholino (MO) in zebrafish embryos in Tg(fli1:EGFP, gata1a: dsRed) leads to intersegmental vessel (Se) remodeling. A - Graphical representation of dose dependent microinjection ranging from 10–500 μM of miR-142a-3p morpholino (MO) in 28–30 hpf Tg(fli1:EGFP, gata1a: dsRed) zebrafish embryos. Bar graph showing percentage of embryos with survival (grey) and intersegmental vessel (Se) defect (black). Numbers of embryos analyzed are indicated in parenthesis. B–G Representative image of Tg(fli1:EGFP, gata1a: dsRed) zebrafish embryos displaying intersegmental vessels (Se) from non-injected control and 200 μM miR-142a-3p morpholino injected embryos at different developmental stages. Images are arranged in a lateral view and displaying intersegmental vessels (Se) from the trunk region. Arrowheads indicate regions with vascular defects.

Acknowledgments

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