ZFIN Image: Dougherty et al., 2013, Fig. 2

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Figure Caption

Fig. 2 wnt9a knockdown results in failure of maxillary extension. (A,B) wnt9a knockdown in the col2a:GFP transgenic (B) produced an ethmoid plate similar to that seen by Alcian Blue stain (inset, B). (C,D) EdU staining from 55-60 hpf revealed a proliferative front in the leading edge of the extending ethmoid plate during palatogenesis (arrowhead, C), but absence of new cell divisions in morphants (D). (E,F) TUNEL assay shows the shortened ethmoid plate (outlined) is not a result of increased cell death. (G,H) When maxillary process CNCCs were labeled by kaede photoconversion before maxillary extension (bracket, G), they failed to extend significantly by 4.5 dpf (H). All images are ventral views, anterior leftwards.

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Acknowledgments

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