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Figure Caption
Fig. 7 INPP5E mutants in zebrafish eye development. (A) Zebrafish embryos were injected with Inpp5e MO (4 ng), Inpp5e MO (4 ng) and hINPP5E WT mRNA (500 pg), Inpp5e MO (4 ng) and hINPP5E R378C mRNA (500 pg), or Inpp5e MO (4 ng) and hINPP5E R435Q mRNA (500 pg). The ventral sides of morphants are shown, scale bar 100 µm. (B) Quantification of eye size of morphants at 24 hpf and 48 hpf (N = 20 embryos, three independent experiments, unpaired t-test, * p = 3.6E08).
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Reprinted from Vision Research, 75, Luo, N., Lu, J., and Sun, Y., Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafish, 98-107, Copyright (2012) with permission from Elsevier. Full text @ Vision Res.