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Fig. s4 High levels of Psmad1,5,8 are induced cell autonomously in caBMPr transgenic cells causing robust changes of neural marker expression (A-C) Animal view of a mid gastrula caBMPr mosaic embryo stained for P-smad1,5,8 in red, shield to the right. Arrows point to single caBMPr-transgenic cells (green cells) in the dorsal half of the embryo which ectopically induce nuclear P-smad1,5,8 (red) in a cell autonomous manner. (D) Statistical analysis of repressed and induced gene expression in caBMPr cells, respectively. n=number of cells/ number of embryos. (tel, telencephalon; NP, neural plate).
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Reprinted from Developmental Cell, 23(4), Bielen, H., and Houart, C., BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis, 812-822, Copyright (2012) with permission from Elsevier. Full text @ Dev. Cell