ZFIN Image: Bielen et al., 2012, Fig. 4

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Figure Caption

Fig. 4

Repression of Anterior Neural Plate Markers by Elevated BMP Activity Is Limited to the Early Stage of GastrulationAll embryos were injected with HSP70:caBMPr plasmid at one- to two-cell stage followed by heat shock at oblong/early blastula stage (A–F) or shield/early gastrula stage (G and H) and fixed at bud stage. Heat shock induction of caBMPr at oblong stage represses foxg1 expression non-cell-autonomously (arrows in A and B) and rx3 expression cell autonomously (arrows in C and D). Dlx3 is ectopically induced in caBMPr-expressing cells inside the neural plate (arrows in E and F). Heat shock at shield stage does not affect rx3 expression (arrows in G and H). All figures are z-projections of confocal sections.

Acknowledgments

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Reprinted from Developmental Cell, 23(4), Bielen, H., and Houart, C., BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis, 812-822, Copyright (2012) with permission from Elsevier. Full text @ Dev. Cell