ZFIN Image: Li et al., 2012, Fig. 3

Image

Figure Caption

Fig. 3 tango^hkz5 mutation causes an increased apoptosis and a decreased proliferation of HSPCs. (A-F) Double immunostaining of CD41-eGFP and TUNEL reveals a slight increase of apoptosis of CD41-eGFP⁺ cells in the CHT of 3 dpf tango^hkz5^/^hkz5 mutant zebrafish embryos. Arrows show the CD41-eGFP⁺ and TUNEL⁺ cells. (G-L) Double immunostaining of CD41-eGFP and BrdU shows a reduced proliferation of CD41-eGFP⁺ cells in the CHT of 3 dpf tango^hkz5^/^hkz5 mutant embryos. (M) Quantification of the percentage of TUNEL⁺ cells in the 3 dpf CD41-eGFP⁺ cell populations. (N) Quantification of the percentage of BrdU⁺ cells in the 3 dpf CD41-eGFP⁺ population. Error bars represent s.e.m.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development