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Fig. S7 Additional validation of mutants supported their computed identities. (A) We observed a dose-dependent phenocopy of the mutant phenotypes with morpholinos against lmx1b and jag1b. (B-D) Compared with wild type (B), the ear phenotypes of mibta52b/ta52b (C) and jag1bjj59/jj59 (D) resemble one another and support the overlapping roles for both gene products in Notch signaling. (E) RT-PCR of cdh23 transcript in wild type, sibling and mutant reveals mis-splicing in an158-3(cdh23nl9) transcripts.
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