ZFIN Image: Matsui et al., 2012, Fig. 2

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Figure Caption

Fig. 2 Overexpression of celf1 results in failures of LR asymmetric patterning. (A,B) Representative images showing left- (mRFP; A) or right- (Celf1; B) sided expression of pitx2a in zebrafish embryos at 18-19 hpf. Dorsal view, anterior to the top. Arrows indicate pitx2a expression in the lateral plate mesoderm. (C) Percentages of left-sided, right-sided, bilateral, or no (absent) expression of pitx2a in mRFP- (n=92), celf1-(n=102) or celf1^Δ^linker- (n=55) overexpressing embryos. (D,E) Representative images of mlc2a expression showing D-loop (mRFP; D) or L-loop (Celf1; E) of the heart in embryos at 42-45 hpf. Ventral view, anterior to the top. A, atrium; V, ventricle. (F) Percentages of D-loop, L-loop, no-loop or cardia bifida of the heart in mRFP- (n=92), celf1-(n=102) or celf1^Δ^linker- (n=51) overexpressing embryos. Scale bars: 200 μm.

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