ZFIN Image: Eom et al., 2012, Fig. 8

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Figure Caption

Fig. 8

Melanophore precursors require igsf11 for their migration and survival.

(A) Selected frames from time-lapse movies of mitfa:GFP+ cells in wild-type and seurat mutant explants. A single cell (red arrow) moved from dorsal to ventral over the duration of the movie. In a seurat mutant, many cells failed to migrate (e.g., red arrow) or died (yellow arrow) during the period of imaging. (B) Velocities (mean±SE) of mitfa:GFP+ cells were significantly reduced in seurat mutants compared to the wild-type (t = 11.2, d.f. = 135), as were total distances traveled (not shown). (C) seurat mutant melanophores were also significantly more likely to die than were wild-type melanophores (X² = 29.8, d.f. = 1).

Acknowledgments

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