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Fig. S5 Reduction in mural cell coverage of ventral head vessels in βPix morphants and itgav/b8 double morphants
Double transgenic Tg(αSMA:GFP)ca7; Tg(kdrla:mCherry)ci5 zebrafish expressing GFP under the mural cell αSMA promoter and mCherry under the endothelial kdrla promoter were injected with a morpholino to either βPix or morpholinos to itgav and itgb8 and assayed at 4 dpf for mural cell presence. Stars mark mural cells in an equivalent vessel in all panels. Abbreviations: va, ventral aorta; paa, pharyngeal arch artery.
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Reprinted from Developmental Biology, 363(1), Liu, J., Zeng, L., Kennedy, R.M., Gruenig, N.M., and Childs, S.J., betaPix plays a dual role in cerebral vascular stability and angiogenesis, and interacts with integrin alphavbeta8, 95-105, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.