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Fig. 1
Morpholino-mediated global knockdown of ctnnb1 or ctnnb2 leads to multiple LR defects in zebrafish embryos. (A-M) One-cell embryos were injected with individual morpholinos and examined for cmlc2 expression in the heart at 30 hpf (A-D) and at 48 hpf (E-H), and foxa3 in visceral organs at 48 hpf (I-M). Embryos representing different classes of phenotypes were in shown in dorsal (A-C,I-L) or ventral (E-G) views. Statistical data are shown in D,H,M, with the total observed number (n) indicated. V, ventricle; A, atria; l, liver; p, pancreas; g, gut. Scale bars: 100 μm.
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