Fig. S7
Codepletion of Ipk1 and either IFT88 or IFT57 synergistically perturbs LR asymmetry. Embryos obtained from crossing wild-type fish were injected with varying amounts of either single MO (ipk1MO1, ift88MO, ift57MO, control MO) or a MO combination (ipk1MO1 + ift88MO, ipk1MO1 + ift57MO, control MO + ift88MO, control MO + ift57MO). On the other hand, embryos derived from crossing heterozygous ift88 (previously known as polaris or oval) mutant (ift88+/-) fish were injected with varying amounts of either ipk1MO1 or control MO. Scores on the heart-tube placement defect in embryos at 28 hpf from each treatment are presented as bar graphs.