Fig. S5
Effect of neucrin on AP patterning and non-neuronal differentiation. (A–D) The expression of otx2 (A and B) and krox20 (C and D) in wild-type (A and C) and neucrin MO1-injected (B and D) embryos at 19 hpf. Lateral view with anterior to the left. (E–H) The expression of otx2 (E and F) and rx3 (G and H) in wild-type (E and G) and neucrin MO1-injected (F and H) embryos at 10 hpf. Dorsal view with anterior to the top. (I and J) The expression of ntla in wild-type (I) and neucrin MO1-injected (J) embryos at 11 hpf. Dorsal view with anterior to the top. (K and L) The expression of dlx2a in wild-type (K) and neucrin MO1-injected (L) embryos at 16 hpf. Lateral view with anterior to the left. Scale bar: 100 μm.
Reprinted from Mechanisms of Development, 128(11-12), Miyake, A., Nihno, S., Murakoshi, Y., Satsuka, A., Nakayama, Y., and Itoh, N., Neucrin, a novel secreted antagonist of canonical Wnt signaling, plays roles in developing neural tissues in zebrafish, 577-590, Copyright (2012) with permission from Elsevier. Full text @ Mech. Dev.