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Fig. S4 Inhibition of apoptosis in mob;mos embryos by p53-MO injection. TUNEL assay in wild-type (WT) embryos (A), mob embryos injected with foxd3 morpholino (B) and mob embryos injected with both foxd3 and p53 morpholinos (C) at 10 hpf shown in dorsal view with anterior side up. p53 knockdown largely reduces apoptosis in embryos without Tfap2a and Foxd3 function.
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Reprinted from Developmental Biology, 360(1), Wang, W.D., Melville, D.B., Montero-Balaguer, M., Hatzopoulos, A.K., and Knapik, E.W., Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population, 173-85, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.