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Fig. S1 foxd3-MO knockdown in mutant mob embryos replicates the phenotype of mob;mos embryos. (A, B) Lateral view of live mob;mos (A) and foxd3-MO knockdown mob (mob + foxd3-MO) (B) embryos at 5 dpf. The two phenotypes show comparable lack of all skin pigmentation and concave heads in the ventral part. (C, D) Ventral view of Alcian blue-stained craniofacial skeleton in mob;mos (C) and foxd3-MO knockdown mob (D) embryos at 5 dpf. In both cases, pharyngeal cartilage is absent and the neurocranium is deformed.
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Reprinted from Developmental Biology, 360(1), Wang, W.D., Melville, D.B., Montero-Balaguer, M., Hatzopoulos, A.K., and Knapik, E.W., Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population, 173-85, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.