ZFIN Image: Wong et al., 2012, Fig. S6

Image

Figure Caption

Fig. S6

CyA treatment results in strong reduction in ptc1 expression.

(A-C). Neural ptc1 expression at the 18-somite stage (arrows) is not affected in the embryos that were CyA-treated from the 30% epiboly to the shield stage (4.5-6hpf, B) but is nearly completely absent in the embryos that were continuously incubated in CyA-solution from the 30% epiboly stage (C) as compared to DMSO-treated controls (A). Dorsal view, anterior is to the left. (D-F) CyA-treatment from the 19-somite stage (F) results in a similar reduction in ptc1 expression (arrows) as the treatment from the 30% epiboly stage (E) as compared to DMSOtreated controls (D). Embryos at the 25-somite stage, lateral view, anterior is to the left.

Acknowledgments

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Reprinted from Developmental Biology, 361(2), Wong, K.S., Rehn, K., Palencia-Desai, S., Kohli, V., Hunter, W., Uhl, J.D., Rost, M.S., and Sumanas, S., Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish, 377-91, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.