Image
|
Figure Caption
Fig. S2
Activation of both ERK and AKT pathways in advanced liver cancer of krasV12 transgenic fish. Driver-effector fish induced with mifepristone (RU486) for more than 8 weeks developed hepatoblastoma (HB) and ascites in mixed HCC. (A) Immunohistochemistry for PERK1/ 2 and P-AKT showing positive nuclear and cytoplasmic staining of both P-ERK1/2 and PAKT proteins in HB (dotted area). (B) Ascites and cyst fluid in mixed HCC also displaying strong expression of P-ERK1/2 and P-AKT protein.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Dis. Model. Mech.