ZFIN Image: Carten et al., 2011, Fig. 2

Image

Figure Caption

Fig. 2 BODIPY-FL C₁₂ is absorbed and transported in the digestive organs of zebrafish larvae. A. The analog appears in the intestinal lumen as well as in lipid droplets in intestinal enterocytes. Diffuse cellular accumulation of BODIPY-FL C₁₂ is consistent with the analog′s shorter chain length, decreased hydrophobicity, faster metabolism, and entry into more subcellular compartments. B. BODIPY-FL C₁₂ readily accumulates in the liver, visualizing large lipid droplets (filled arrowhead), hepatic ducts (arrow), and hepatocyte nuclei (empty arrowhead). C. BODIPY-FL C₁₂ accumulates in fluorescent foci (arrowhead) in the exocrine pancreas. A Scale bars = 10μm. (n = 3; 6 larvae per feed.)

Acknowledgments

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Reprinted from Developmental Biology, 360(2), Carten, J.D., Bradford, M.K., and Farber, S., Visualizing digestive organ morphology and function using differential fatty acid metabolism in live zebrafish, 276-85, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.