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Fig. 2 Expression of apical ectodermal markers at 28 h (A,B,E) and 38 h (C,D,F,G,H,I,K-N). Anterior is towards the left, distal is towards the top. (J) shows the expression at 49 h: distal is towards the right, dorsal is towards the top. (A,C,F,H,J,K,M) wt, (B,D,G,I,L) dak-, (E) wt and dak- are indistinguishable, (N) syut4. (A-D) expression of dlx2. (E-G) expression of bmp2. (H-J,M,N) expression of fgf4. (K,L) expression of fgf8. dlx2 and bmp2 are activated at 28 h but their expression is strongly reduced at 38 h in dak-. Both fgfs are not properly activated in dak-. fgf4 is not expressed in syut4.
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