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Fig. S1 Phenotypes of cug2 translation blocking morpholino (ATG-MO) in zebrafish embryos. A, B. cug2 MO-injected embryo (B) shows developmental defects including flat head, pinched midbrain-hindbrain boundary (arrowhead), thin yolk extension (arrow), and curved-up body. C, D. The translation blocking MO (ATG-MO) specifically inhibits the translation of cug2-GFP mRNA containing its targeting region. E, F. DIC image of PTU-treated cug2 morphant. The cug2 morphant shows retina degeneration and pinched brain structure (arrow) at 3 dpf. ov, otic vesicle; ret, retina. Scale bars = 200 μm.
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Full text @ BMC Dev. Biol.