ZFIN Image: Lewis et al., 2011, Fig. 7

Image

Figure Caption

Fig. 7

The number of GABA receptor puncta is increased on celsr3 mutant ON-bipolar terminals.

A) ON-bipolar cells in cryosection were stained with anti-PKC antibodies and anti-GABAγ2. The PKC label fields were overlayed on the GABA signal, and the number of puncta was counted in each terminal rotated and visualized in 3D. Image shows merged z-stacks. Scale bars are 5 μm. B) The GABA puncta in the ON-bipolar terminals per μm³ for WT and celsr3 mutants (n = 60 terminals for each). Error bars are standard error. C) Mosaic 2 dpf larva containing WT cells in the eye (yellow dashed line) of a celsr3 mutant animal. Despite a large WT eye field transplant, this animal remained OKR negative. The tan dashed line outlines larva body.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.