ZFIN Image: Kapsimali et al., 2011, Fig. 7

Image

Figure Caption

Fig. 7

Activation of Notch signaling maintains taste bud Calb2b⁺ but not 5HT⁺ cells. (A) Heatshock treatment in HsNicd siblings. (B-G) Embryonic stage and scale bar are in the bottom left-hand corner and marker expression is in the bottom right-hand corner. Anterior is towards the left. Ventral views of whole-mounted larvae heads. Asterisks indicate taste buds in the lips. Note the absence of 5HT (C) and maintenance of Calb2b (E) and miR-200b (G) expression in the Hsnicd-expressing embryos compared with wild-type (heatshocked) siblings. Hsnicd embryos were identified by anti-myc (red, C,E) immunohistochemistry or genotyped after in situ hybridization (G). Scale bars: 12 μm. b1-b5, branchial arches 1-5; e, eye; h, hyoid arch; m, mandibular arch; nm, neuromast; oe, olfactory epithelium.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development