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Fig. s4
Hyperactive RAR-vps induce regional activation of the RARE reporter. Tg(12XRARE-ef1a:gfp) embryos overexpressing RAR-vps. (A) Control uninjected embryos and embryos injected with (B) rarab-Nvp, (C) rarab-ΔAvp, (D) rarab-Cvp, (E) rarab-ΔFvp, (F) rarga-Nvp, (G) rargaΔAvp, and (H) rargaΔFvp mRNAs. Reporter expression is enhanced in regions of the embryo near a source of RA. Arrow in C indicates expanded ventral eye expression. Arrowhead in C indicates reporter expression within the trunk. All images are lateral views, with anterior up and dorsal to the right.
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Reprinted from Developmental Biology, 352(1), Waxman, J.S., and Yelon, D., Zebrafish retinoic acid receptors function as context-dependent transcriptional activators, 128-140, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.