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Fig. 5 Nrz Knockdown Leads to Profound Alterations of the Cytoskeleton Inside the Yolk Cell
(A) F-actin staining in control embryos and nrz morphants at 40%–50% epiboly stage showing the status of cortical F-actin inside the vegetal pole (white asterisk). In nrz morphants, cortical actin is severely reduced or absent.
(B) Histogram showing the percentage of control embryos versus nrz morphants at 50% epiboly stage with normal (blue), reduced (red), or absent (green) cortical F-actin. See also Figure S4.
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Reprinted from Developmental Cell, 20(5), Popgeorgiev, N., Bonneau, B., Ferri, K.F., Prudent, J., Thibaut, J., and Gillet, G., The Apoptotic Regulator Nrz Controls Cytoskeletal Dynamics via the Regulation of Ca(2)+ Trafficking in the Zebrafish Blastula, 663-676, Copyright (2011) with permission from Elsevier. Full text @ Dev. Cell