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Fig. 3
Expression of cxcl12b and cxcr4a in the zebrafish hindbrain. (A-D) Two-color fluorescent in situ hybridization showing the distribution of kdrl mRNA (green) and cxcl12b (A) and cxcr4a (B-D) mRNA (red). Lateral views, anterior to the left. (A) cxcl12b and kdrl expression at 36 hpf. Inset indicates the plane of view in A and B. (B) cxcr4a and kdrl expression at 36 hpf. Arrowhead indicates a single cxcr4a-expressing CtA sprout. (C) cxcr4a and kdrl expression at 48 hpf. Arrowheads indicate tip cells of CtA sprouts expressing cxcr4a. (D) Enlargement of the boxed area in C. The kdrl-positive endothelial cells are outlined.