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Fig. S5 Abnormal endocrine pancreas localization in pk1a morphants. Wholemount in situ hybridization of insulin (ins), an endocrine pancreas marker, in 3 dpf control (A) and pk1a morphants demonstrates abnormal exocrine pancreas location, including “abnormal” (B, C), and “left” (D). (E) Graph depicting the scoring of pk1a morphants demonstrates a significant difference in the localization of the endocrine pancreas (p<0.0001 by chi-square test). When combined with the localization of try, there is a significant difference in the localization of the pancreas in pk1a morphants (p<0.0001).
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Reprinted from Developmental Biology, 351(2), Cui, S., Capecci, L.M., and Matthews, R.P., Disruption of planar cell polarity activity leads to developmental biliary defects, 229-241, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.