Image
|
Figure Caption
Fig. 9 in situ hybridization for mitfa in wild-type (A,B) and mitfafh53 (C,D) larvae held at restrictive temperature with or without AG1478 treatment from 9 to 48 hour development. AG1478 treatment reduces the number of mitfa-expressing cells in both wild-type and mutant embryos. Larvae are at the equivalent of the 65 hour stage at standard temperature. Embryos were treated with 0.2 mM PTU to suppress melanin synthesis.
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 350(2), Johnson, S.L., Nguyen, A.N., and Lister, J.A., mitfa is required at multiple stages of melanocyte differentiation but not to establish the melanocyte stem cell, 405-413, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.