ZFIN Image: Ravanelli et al., 2011, Fig. S6

Image

Figure Caption

Fig. S6 Primary cilia length is unaffected in cobl morphants.

Cilia in eight somite stage and 48 hpf embryos were stained with anti-acetylated tubulin and analyzed for length. Motile monocilia in Kupffer′s vesicle are reduced in length in cobl morphants (B–C) relative to controls (A). In contrast, primary cilia present on cells surrounding the KV appear unaffected in length and distribution. Motile cilia in the pronephros are reduced in length in cobl morphants (E) relative to controls (D). As before, primary cilia present in tissues surrounding the pronephros appear unaffected in length and distribution. Dashed lines outline the region magnified in the insert. Arrows point to primary cilia magnified from surrounding tissue. Kupffer′s vesicle (KV) outlined in dotted line. Multi-ciliated cells in D-E marked with an asterisk. Neuronal axons marked with an ‘n.’ Scale bars represent 10 μm.

Acknowledgments

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Reprinted from Developmental Biology, 350(1), Ravanelli, A.M., and Klingensmith, J., The Actin Nucleator Cordon-bleu is Required for Development of Motile Cilia in Zebrafish, 101-111, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.