ZFIN Image: Scholpp et al., 2009, Fig. S3

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Figure Caption

Fig. S3 Her6 inhibits expression of the proneural gene coe2 and neurog1. Analysis of Her6 function by double ISH. Knock-down of her6 leads to an increase of coe2 expression in the thalamic complex at 30 hpf (a and b). A double in situ hybridization analysis shows that mis-expression of her6 mRNA leads to the down-regulation of neurog1 expression in the thalamus at 24 hpf (c and d; black dashed line). Expression of ascl1a in the ventral part is increased (yellow dashed line). Subsequently, ascl1a expression is increased upon her6 mis-expression at 30 hpf (22/35; f and g). cTh, caudal thalamus; PTh, prethalamus; rTh, rostral thalamus; Th, thalamus.

Acknowledgments

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