ZFIN Image: Murata et al., 2010, Fig. S5

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Figure Caption

Fig. S5 Caudal shift in pelvic fins observed in embryos injected with gdf11 MO. (A, B) Schematic diagrams of zebrafish larvae at 6 wpf. Zebrafish morphants were injected with 5 ng control MO (A) or 10 ng gdf11 MO (B). (A′, B′) Confocal micrographs of morphants labeled with anti-paxillin to visualize the different segments. Numbers in the panels indicate the segmental order. Note that prospective pelvic fin muscle regions (anterior regions of fins) of gdf11 morphants are attached to the 10th segment (white arrowhead in A′), while those of control morphants are attached to the 9th segment (white arrowhead in B′). (C) Percentages of larvae with pelvic fins at the somite 9 or 10 level following injection of 5 ng control MO, 10 ng gdf11 MO, or 4 ng gdf11 MO. pel, pelvic fin. Scale bars: 500 μm for panels (A) and (B).

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Acknowledgments

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Reprinted from Developmental Biology, 347(1), Murata, Y., Tamura, M., Aita, Y., Fujimura, K., Murakami, Y., Okabe, M., Okada, N., and Tanaka, M., Allometric growth of the trunk leads to the rostral shift of the pelvic fin in teleost fishes, 236-245, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.