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Figure Caption
Fig. 8 Id2a levels modulate retinoblast proliferation in vivo. (A) Kaede clonal analysis paradigm. (B-G) Clonal expansion between 30 and 39 hpf in Id2a-MM (B,E), Id2a-MO (C,F) and id2a mRNA retinas (D,G). Projections from confocal z-stacks with the approximate position of each clone outlined. (H) Quantification of fold increase in cell number per clone (n=3 retinas). Id2a-MM clones exhibit a 1.7-fold increase in cell number, Id2a-MO clones exhibit a 1.29-fold increase (**, P=0.0019), and id2a-overexpressing clones exhibit a 2.45-fold increase (***, P=0.002) over time. Error bars indicate ± s.e.m.
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