ZFIN Image: Matsuda et al., 2010, Fig. 2

Image

Figure Caption

Fig. 2 The pLLp eventually undergoes fragmentation when Notch signaling is lost. Images from time-lapse (started at <32 hpf) of (A) wild-type, (B) mib1^ta52b and (C) N1/N3MO/DAPT tg[cldnb:lynGFP] zebrafish embryos. (A) In wild type, the pLLp migrates as a cohesive structure (bracket); a single break (arrowhead) allows deposition of a neuromast. See Movie 1 in the supplementary material. (B,C) The pLLp fragments as ectopic breaks develop (arrowheads), and proneuromasts are prematurely deposited in both mib1^ta52b and N1/N3MO/DAPT embryos. A small portion of the remaining pLLp (bracket) continues to migrate. See Movies 3 and 4 in the supplementary material.

Acknowledgments

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