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Fig. S7 Mind bomb-Jagged 1 signalling is required for the development of non-vacuolated cells with abundant rough ER. The number of non-vacuolated cells stained by an anti-KDEL antibody was reduced in the jag1a/1b-knockdown and mib mutant embryos, but not in deltaA/D-knockdown embryos. The ER was stained with an anti-KDEL antibody (green), and nuclei were revealed by DAPI staining (magenta). Arrows indicate anti-KDEL-positive non-vacuolated cells. Side views of the ventral regions of the notochord in embryos on day 2 are shown.
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